With the chances of finishing in the top four all but over, there is no doubt that Moyes will take United into this game with only one thing on his agenda, the return leg against Bayern Munich in the Champions League.
With the entire season resting on this game in mid-week, and Moyes´ habitual tendency to make vast changes in every game he takes control of, it is likely that almost all of the players that will be in contention for the Munich game will be rested for this one.
As has been previously mentioned, it is debatable wheter United really want to finish any higher than seventh, as a Europa Cup run will merely disrupt a serious challenge for a top four place next season, and David Moyes must finish in the top four next year to have any hope of keeping his job.
If Tottenham continue to freefall under Sherwood, United may just sneak into sixth over the next few weeks and this will most likely not be welcomed by many inside Old Trafford, although this would never be spoken of publicly of course.
So as United United travel to St James Park, we can expect starts for Nani, Hernandez and Kagawa amongst others. Rooney will most likely be rested although as has been proven, the more he plays, the better his form. Mata will of course start due to his ineligibility for the Champions League.
United should still have more than enough to take care of a struggling Newcastle side who have seemed lost without Alan Pardew on the sidelines throwing head butts around.